Multi-omics reveal specific targets of the RNA-binding protein Puf3p and its orchestration of mitochondrial biogenesis

Coenzyme Q (CoQ) is a redox-active lipid required for mitochondrial oxidative phosphorylation (OxPhos). How CoQ biosynthesis is coordinated with the biogenesis of OxPhos protein complexes is unclear. Here, we show that the Saccharomyces cerevisiae RNA-binding protein (RBP) Puf3p regulates CoQ biosyn...

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Publicado en:Cell Syst
Main Authors: Lapointe, Christopher P., Stefely, Jonathan A., Jochem, Adam, Hutchins, Paul D., Wilson, Gary M., Kwiecien, Nicholas W., Coon, Joshua J., Wickens, Marvin, Pagliarini, David J.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799006/
https://ncbi.nlm.nih.gov/pubmed/29248374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.11.012
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