Mitochondrial protein functions elucidated by multi-omic mass spectrometry profiling

Mitochondrial dysfunction is associated with many human diseases, including cancer and neurodegeneration, that are often linked to proteins and pathways that are not well-characterized. To begin defining the functions of such poorly characterized proteins, we used mass spectrometry to map the proteo...

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Gepubliceerd in:Nat Biotechnol
Hoofdauteurs: Stefely, Jonathan A., Kwiecien, Nicholas W., Freiberger, Elyse C., Richards, Alicia L., Jochem, Adam, Rush, Matthew J. P., Ulbrich, Arne, Robinson, Kyle P., Hutchins, Paul D., Veling, Mike T., Guo, Xiao, Kemmerer, Zachary A., Connors, Kyle J., Trujillo, Edna A., Sokol, Jacob, Marx, Harald, Westphall, Michael S., Hebert, Alexander S., Pagliarini, David J., Coon, Joshua J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101133/
https://ncbi.nlm.nih.gov/pubmed/27669165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3683
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