Using Mendelian randomization to investigate a possible causal relationship between adiposity and increased bone mineral density at different skeletal sites in children

Background: Lean mass is positively associated with bone mineral density (BMD). However, the relationship between adiposity and BMD is more controversial. In particular, it is unclear if the observational association between the two reflects a causal effect of fat mass on BMD. Previous Mendelian ran...

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Detalles Bibliográficos
Publicado en:Int J Epidemiol
Main Authors: Kemp, John P, Sayers, Adrian, Smith, George Davey, Tobias, Jonathan H, Evans, David M
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
Assuntos:
Mendelian Randomization
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100609/
https://ncbi.nlm.nih.gov/pubmed/27215616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyw079
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