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Examining the Causal Role of Leptin in Bone Mineral Density: A Mendelian Randomization Study

Leptin, a small polypeptide hormone secreted by the adipocytes, controls body weight and gonadal function by binding to a special receptor located in the hypothalamus. Observational studies have demonstrated a controversial association between leptin and bone mineral density (BMD), and functional st...

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Detalhes bibliográficos
Publicado no:Bone
Main Authors: Meng, Xiang-He, Tan, Li-Jun, Xiao, Hong-Mei, Tang, Bei-Sha, Deng, Hong-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686663/
https://ncbi.nlm.nih.gov/pubmed/31077850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.05.006
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