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OGT restrains the expansion of DNA damage signaling

O-linked N-acetylglucosamine linkage (O-GlcNAcylation) to serine or threonine residues regulates numerous biological processes; however, its role in DNA damage response remains elusive. Here, we found that O-GlcNAcylation is induced by DNA damage response. O-GlcNAc transferase (OGT), the solo enzyme...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Chen, Qiang, Yu, Xiaochun
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100584/
https://ncbi.nlm.nih.gov/pubmed/27458206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw663
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