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Inhibition of Alzheimer amyloid β aggregation by polyvalent trehalose
A glycopolymer carrying trehalose was found to suppress the formation of amyloid fibrils from the amyloid β peptide (1–42) (Aβ), as evaluated by thioflavin T assay and atomic force microscopy. Glycopolymers carrying sugar alcohols also changed the aggregation properties of Aβ, and the inhibitory eff...
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| Pubblicato in: | Sci Technol Adv Mater |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5099731/ https://ncbi.nlm.nih.gov/pubmed/27877974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1468-6996/9/2/024407 |
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