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Depression-like phenotype by deletion of α7 nicotinic acetylcholine receptor: Role of BDNF-TrkB in nucleus accumbens

The α7 subtype of nicotinic acetylcholine receptor (nAChR) plays a role in the inflammation which is implicated in depression. This study was undertaken to examine the role of α7 nAChR in depression using α7 nAChR knock-out (KO) mice. Serum levels of tumor necrosis factor-α and interlukin-1β in KO m...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Ji-chun, Yao, Wei, Ren, Qian, Yang, Chun, Dong, Chao, Ma, Min, Wu, Jin, Hashimoto, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099687/
https://ncbi.nlm.nih.gov/pubmed/27821848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36705
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