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Adjunctive treatment of brexpiprazole with fluoxetine shows a rapid antidepressant effect in social defeat stress model: Role of BDNF-TrkB signaling

Addition of low doses of the atypical antipsychotic drug brexpiprazole with selective serotonin reuptake inhibitors (SSRIs) could promote antidepressant effect in patients with major depressive disorder although the precise mechanisms underlying the action of the combination are unknown. Combination...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ma, Min, Ren, Qian, Yang, Chun, Zhang, Ji-chun, Yao, Wei, Dong, Chao, Ohgi, Yuta, Futamura, Takashi, Hashimoto, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171769/
https://ncbi.nlm.nih.gov/pubmed/27991542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39209
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