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Population pharmacokinetics of doxorubicin and doxorubicinol in patients diagnosed with non‐Hodgkin's lymphoma

AIMS: The aims of the study were: (i) to characterize the pharmacokinetics (PK) of doxorubicin (DOX) and doxorubicinol (DOXol) in patients diagnosed with non‐Hodgkin's lymphoma (NHL) using a population approach; (ii) to evaluate the influence of various covariates on the PK of DOX; and (iii) to...

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Publicado en:Br J Clin Pharmacol
Autores principales: Pérez‐Blanco, Jonás Samuel, Santos‐Buelga, Dolores, Fernández de Gatta, María del Mar, Hernández‐Rivas, Jesús María, Martín, Alejandro, García, María José
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099548/
https://ncbi.nlm.nih.gov/pubmed/27447545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13070
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