Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA

Cockayne syndrome is a neurodegenerative accelerated aging disorder caused by mutations in the CSA or CSB genes. Although the pathogenesis of Cockayne syndrome has remained elusive, recent work implicates mitochondrial dysfunction in the disease progression. Here, we present evidence that loss of CS...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Scheibye-Knudsen, Morten, Tseng, Anne, Borch Jensen, Martin, Scheibye-Alsing, Karsten, Fang, Evandro Fei, Iyama, Teruaki, Bharti, Sanjay Kumar, Marosi, Krisztina, Froetscher, Lynn, Kassahun, Henok, Eckley, David Mark, Maul, Robert W., Bastian, Paul, De, Supriyo, Ghosh, Soumita, Nilsen, Hilde, Goldberg, Ilya G., Mattson, Mark P., Wilson, David M., Brosh, Robert M., Gorospe, Myriam, Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098674/
https://ncbi.nlm.nih.gov/pubmed/27791127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610198113
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