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Autotaxin-mediated lipid signaling intersects with LIF and BMP signaling to promote the naive pluripotency transcription factor program

Developmental signaling molecules are used for cell fate determination, and understanding how their combinatorial effects produce the variety of cell types in multicellular organisms is a key problem in biology. Here, we demonstrate that the combination of leukemia inhibitory factor (LIF), bone morp...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Kime, Cody, Sakaki-Yumoto, Masayo, Goodrich, Leeanne, Hayashi, Yohei, Sami, Salma, Derynck, Rik, Asahi, Michio, Panning, Barbara, Yamanaka, Shinya, Tomoda, Kiichiro
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098653/
https://ncbi.nlm.nih.gov/pubmed/27738243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608564113
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