Autotaxin-mediated lipid signaling intersects with LIF and BMP signaling to promote the naive pluripotency transcription factor program

Developmental signaling molecules are used for cell fate determination, and understanding how their combinatorial effects produce the variety of cell types in multicellular organisms is a key problem in biology. Here, we demonstrate that the combination of leukemia inhibitory factor (LIF), bone morp...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Kime, Cody, Sakaki-Yumoto, Masayo, Goodrich, Leeanne, Hayashi, Yohei, Sami, Salma, Derynck, Rik, Asahi, Michio, Panning, Barbara, Yamanaka, Shinya, Tomoda, Kiichiro
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2016
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098653/
https://ncbi.nlm.nih.gov/pubmed/27738243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608564113
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