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Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responses
Although p53-mediated cell-cycle arrest, senescence, and apoptosis remain critical barriers to cancer development, the emerging role of p53 in cell metabolism, oxidative responses, and ferroptotic cell death has been a topic of great interest. Nevertheless, it is unclear how p53 orchestrates its act...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5098629/ https://ncbi.nlm.nih.gov/pubmed/27698118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607152113 |
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