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Molecular lock regulates binding of glycine to a primitive NMDA receptor

The earliest metazoan ancestors of humans include the ctenophore Mnemiopsis leidyi. The genome of this comb jelly encodes homologs of vertebrate ionotropic glutamate receptors (iGluRs) that are distantly related to glycine-activated NMDA receptors and that bind glycine with unusually high affinity....

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yu, Alvin, Alberstein, Robert, Thomas, Alecia, Zimmet, Austin, Grey, Richard, Mayer, Mark L., Lau, Albert Y.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098608/
https://ncbi.nlm.nih.gov/pubmed/27791085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607010113
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