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Differential selective pressure alters rate of drug resistance acquisition in heterogeneous tumor populations
Recent drug discovery and development efforts have created a large arsenal of targeted and chemotherapeutic drugs for precision medicine. However, drug resistance remains a major challenge as minor pre-existing resistant subpopulations are often found to be enriched at relapse. Current drug design h...
Tallennettuna:
| Julkaisussa: | Sci Rep |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5098152/ https://ncbi.nlm.nih.gov/pubmed/27819268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36198 |
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