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Cationic bactericidal peptide 1018 does not specifically target the stringent response alarmone (p)ppGpp

The bacterial stringent response is a key regulator of bacterial virulence, biofilm formation and antibiotic tolerance, and is a promising target for the development of new antibacterial compounds. The intracellular nucleotide (p)ppGpp acts as a messenger orchestrating the stringent response. A synt...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Andresen, Liis, Tenson, Tanel, Hauryliuk, Vasili
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098146/
https://ncbi.nlm.nih.gov/pubmed/27819280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36549
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