mTOR Overactivation in Mesenchymal cells Aggravates CCl(4)− Induced liver Fibrosis

Hepatic stellate cells are of mesenchymal cell type located in the space of Disse. Upon liver injury, HSCs transactivate into myofibroblasts with increase in expression of fibrillar collagen, especially collagen I and III, leading to liver fibrosis. Previous studies have shown mTOR signaling is acti...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Shan, Lanlan, Ding, Yan, Fu, You, Zhou, Ling, Dong, Xiaoying, Chen, Shunzhi, Wu, Hongyuan, Nai, Wenqing, Zheng, Hang, Xu, Wanfu, Bai, Xiaochun, Jia, Chunhong, Dai, Meng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098141/
https://ncbi.nlm.nih.gov/pubmed/27819329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36037
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