Solute Carrier NTCP Regulates Innate Antiviral Immune Responses Targeting Hepatitis C Virus Infection of Hepatocytes

Chronic hepatitis B, C, and D virus (HBV, HCV, and HDV) infections are the leading causes of liver disease and cancer worldwide. Recently, the solute carrier and sodium taurocholate co-transporter NTCP has been identified as a receptor for HBV and HDV. Here, we uncover NTCP as a host factor regulati...

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Foilsithe in:Cell Rep
Main Authors: Verrier, Eloi R., Colpitts, Che C., Bach, Charlotte, Heydmann, Laura, Zona, Laetitia, Xiao, Fei, Thumann, Christine, Crouchet, Emilie, Gaudin, Raphaël, Sureau, Camille, Cosset, François-Loïc, McKeating, Jane A., Pessaux, Patrick, Hoshida, Yujin, Schuster, Catherine, Zeisel, Mirjam B., Baumert, Thomas F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cell Press 2016
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098118/
https://ncbi.nlm.nih.gov/pubmed/27783949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.09.084
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