Functional Analysis of Claudin-6 and Claudin-9 as Entry Factors for Hepatitis C Virus Infection of Human Hepatocytes by Using Monoclonal Antibodies

The relevance of claudin-6 and claudin-9 in hepatitis C virus (HCV) entry remains elusive. We produced claudin-6- or claudin-9-specific monoclonal antibodies that inhibit HCV entry into nonhepatic cells expressing exogenous claudin-6 or claudin-9. These antibodies had no effect on HCV infection of h...

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Hlavní autoři: Fofana, Isabel, Zona, Laetitia, Thumann, Christine, Heydmann, Laura, Durand, Sarah C., Lupberger, Joachim, Blum, Hubert E., Pessaux, Patrick, Gondeau, Claire, Reynolds, Gary M., McKeating, Jane A., Grunert, Fritz, Thompson, John, Zeisel, Mirjam B., Baumert, Thomas F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753993/
https://ncbi.nlm.nih.gov/pubmed/23864633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01691-13
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