EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy

Hepatitis C virus (HCV) is a major cause of liver disease. Therapeutic options are limited and preventive strategies are absent. Entry is the first step of infection and requires the cooperative interaction of several host cell factors. Using a functional RNAi kinase screen we identified epidermal g...

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Bibliografiska uppgifter
Huvudupphovsmän: Lupberger, Joachim, Zeisel, Mirjam B., Xiao, Fei, Thumann, Christine, Fofana, Isabel, Zona, Laetitia, Davis, Christopher, Mee, Christopher J., Turek, Marine, Gorke, Sebastian, Royer, Cathy, Fischer, Benoit, Zahid, Muhammad N., Lavillette, Dimitri, Fresquet, Judith, Cosset, François-Loïc, Rothenberg, S Michael, Pietschmann, Thomas, Patel, Arvind H., Pessaux, Patrick, Doffoël, Michel, Raffelsberger, Wolfgang, Poch, Olivier, Mckeating, Jane A., Brino, Laurent, Baumert, Thomas F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Company 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938446/
https://ncbi.nlm.nih.gov/pubmed/21516087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2341
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