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EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy

Hepatitis C virus (HCV) is a major cause of liver disease. Therapeutic options are limited and preventive strategies are absent. Entry is the first step of infection and requires the cooperative interaction of several host cell factors. Using a functional RNAi kinase screen we identified epidermal g...

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Detalhes bibliográficos
Main Authors: Lupberger, Joachim, Zeisel, Mirjam B., Xiao, Fei, Thumann, Christine, Fofana, Isabel, Zona, Laetitia, Davis, Christopher, Mee, Christopher J., Turek, Marine, Gorke, Sebastian, Royer, Cathy, Fischer, Benoit, Zahid, Muhammad N., Lavillette, Dimitri, Fresquet, Judith, Cosset, François-Loïc, Rothenberg, S Michael, Pietschmann, Thomas, Patel, Arvind H., Pessaux, Patrick, Doffoël, Michel, Raffelsberger, Wolfgang, Poch, Olivier, Mckeating, Jane A., Brino, Laurent, Baumert, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Company 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938446/
https://ncbi.nlm.nih.gov/pubmed/21516087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2341
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