EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy

Hepatitis C virus (HCV) is a major cause of liver disease. Therapeutic options are limited and preventive strategies are absent. Entry is the first step of infection and requires the cooperative interaction of several host cell factors. Using a functional RNAi kinase screen we identified epidermal g...

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Bibliografiset tiedot
Päätekijät: Lupberger, Joachim, Zeisel, Mirjam B., Xiao, Fei, Thumann, Christine, Fofana, Isabel, Zona, Laetitia, Davis, Christopher, Mee, Christopher J., Turek, Marine, Gorke, Sebastian, Royer, Cathy, Fischer, Benoit, Zahid, Muhammad N., Lavillette, Dimitri, Fresquet, Judith, Cosset, François-Loïc, Rothenberg, S Michael, Pietschmann, Thomas, Patel, Arvind H., Pessaux, Patrick, Doffoël, Michel, Raffelsberger, Wolfgang, Poch, Olivier, Mckeating, Jane A., Brino, Laurent, Baumert, Thomas F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Company 2011
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938446/
https://ncbi.nlm.nih.gov/pubmed/21516087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2341
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