A Novel Monoclonal Anti-CD81 Antibody Produced by Genetic Immunization Efficiently Inhibits Hepatitis C Virus Cell-Cell Transmission

BACKGROUND AND AIMS: Hepatitis C virus (HCV) infection is a challenge to prevent and treat because of the rapid development of drug resistance and escape. Viral entry is required for initiation, spread, and maintenance of infection, making it an attractive target for antiviral strategies. METHODS: U...

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Détails bibliographiques
Auteurs principaux: Fofana, Isabel, Xiao, Fei, Thumann, Christine, Turek, Marine, Zona, Laetitia, Tawar, Rajiv G., Grunert, Fritz, Thompson, John, Zeisel, Mirjam B., Baumert, Thomas F.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660333/
https://ncbi.nlm.nih.gov/pubmed/23704981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064221
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