A Novel Monoclonal Anti-CD81 Antibody Produced by Genetic Immunization Efficiently Inhibits Hepatitis C Virus Cell-Cell Transmission

BACKGROUND AND AIMS: Hepatitis C virus (HCV) infection is a challenge to prevent and treat because of the rapid development of drug resistance and escape. Viral entry is required for initiation, spread, and maintenance of infection, making it an attractive target for antiviral strategies. METHODS: U...

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Autores principales: Fofana, Isabel, Xiao, Fei, Thumann, Christine, Turek, Marine, Zona, Laetitia, Tawar, Rajiv G., Grunert, Fritz, Thompson, John, Zeisel, Mirjam B., Baumert, Thomas F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660333/
https://ncbi.nlm.nih.gov/pubmed/23704981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064221
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