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Selective inhibition by a synthetic hirudin peptide of fibrin-dependent thrombosis in baboons.

To determine the importance of the thrombin substrate recognition exosite for fibrinogen binding in the formation of both arterial and venous thrombi, we evaluated the antithrombotic effects of the tyrosine-sulfated dodecapeptide from residues 53-64 of hirudin (H peptide) in a nonhuman primate model...

詳細記述

保存先:
書誌詳細
主要な著者: Cadroy, Y, Maraganore, J M, Hanson, S R, Harker, L A
フォーマット: Artigo
言語:Inglês
出版事項: 1991
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC50980/
https://ncbi.nlm.nih.gov/pubmed/1996320
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