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Potential anti-obesity effects of a long-acting cocaine hydrolase

A long-acting cocaine hydrolase, known as CocH3-Fc(M3), engineered from human butyrylcholinesterase (BChE) was tested, in this study, for its potential anti-obesity effects. Mice on a high-fat diet gained significantly less body weight when treated weekly with 1 mg/kg CocH3-Fc(M3) compared to contro...

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Publicado en:Chem Biol Interact
Main Authors: Zheng, Xirong, Deng, Jing, Zhang, Ting, Yao, Jianzhuang, Zheng, Fang, Zhan, Chang-Guo
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097895/
https://ncbi.nlm.nih.gov/pubmed/27163854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2016.05.010
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