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Cancer-Selective Death of Human Breast Cancer Cells by Leelamine Is Mediated by Bax and Bak Activation

The present study is the first to report inhibition of breast cancer cell growth in vitro and in vivo and suppression of self-renewal of breast cancer stem cells (bCSC) by a pine bark component (leelamine). Except for a few recent publications in melanoma, anticancer pharmacology of this interesting...

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Dettagli Bibliografici
Pubblicato in:Mol Carcinog
Autori principali: Sehrawat, Anuradha, Kim, Su-Hyeong, Hahm, Eun-Ryeong, Arlotti, Julie A., Eiseman, Julie, Shiva, Sruti S., Rigatti, Lora H., Singh, Shivendra V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097706/
https://ncbi.nlm.nih.gov/pubmed/27149078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22497
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