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Cancer-Selective Death of Human Breast Cancer Cells by Leelamine Is Mediated by Bax and Bak Activation

The present study is the first to report inhibition of breast cancer cell growth in vitro and in vivo and suppression of self-renewal of breast cancer stem cells (bCSC) by a pine bark component (leelamine). Except for a few recent publications in melanoma, anticancer pharmacology of this interesting...

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Detalhes bibliográficos
Publicado no:Mol Carcinog
Main Authors: Sehrawat, Anuradha, Kim, Su-Hyeong, Hahm, Eun-Ryeong, Arlotti, Julie A., Eiseman, Julie, Shiva, Sruti S., Rigatti, Lora H., Singh, Shivendra V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097706/
https://ncbi.nlm.nih.gov/pubmed/27149078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22497
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