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Cancer-Selective Death of Human Breast Cancer Cells by Leelamine Is Mediated by Bax and Bak Activation

The present study is the first to report inhibition of breast cancer cell growth in vitro and in vivo and suppression of self-renewal of breast cancer stem cells (bCSC) by a pine bark component (leelamine). Except for a few recent publications in melanoma, anticancer pharmacology of this interesting...

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Détails bibliographiques
Publié dans:Mol Carcinog
Auteurs principaux: Sehrawat, Anuradha, Kim, Su-Hyeong, Hahm, Eun-Ryeong, Arlotti, Julie A., Eiseman, Julie, Shiva, Sruti S., Rigatti, Lora H., Singh, Shivendra V.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097706/
https://ncbi.nlm.nih.gov/pubmed/27149078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22497
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