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Zerumbone causes Bax and Bak-mediated apoptosis in human breast cancer cells and inhibits orthotopic xenograft growth in vivo

The present study was undertaken to determine the anticancer efficacy of zerumbone (ZER), a sesquiterpene from subtropical ginger, against human breast cancer cells in vitro and in vivo. ZER treatment caused a dose-dependent decrease in viability of MCF-7 and MDA-MB-231 human breast cancer cells in...

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Detalhes bibliográficos
Main Authors: Sehrawat, Anuradha, Arlotti, Julie A., Murakami, Akira, Singh, Shivendra V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484218/
https://ncbi.nlm.nih.gov/pubmed/23053663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2280-5
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