IRES inhibition induces terminal differentiation and synchronized death in triple-negative breast cancer and glioblastoma cells

Internal ribosome entry site (IRES)-mediated translation is a specialized mode of protein synthesis which malignant cells depend on to survive adverse microenvironmental conditions. Our lab recently reported the identification of a group of compounds which selectively interfere with IRES-mediated tr...

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Dettagli Bibliografici
Pubblicato in:Tumour Biol
Autori principali: Vaklavas, Christos, Grizzle, William E., Choi, Hyoungsoo, Meng, Zheng, Zinn, Kurt R., Shrestha, Kedar, Blume, Scott W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097113/
https://ncbi.nlm.nih.gov/pubmed/27460074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13277-016-5161-4
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