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Northwestern profiling of potential translation-regulatory proteins in human breast epithelial cells and malignant breast tissues: evidence for pathological activation of the IGF1R IRES

Genes involved in the control of cell proliferation and survival (those genes most important to cancer pathogenesis) are often specifically regulated at the translational level, through RNA-protein interactions involving the 5’-untranslated region of the mRNA. IGF1R is a proto-oncogene strongly impl...

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Detalhes bibliográficos
Main Authors: Blume, Scott W., Jackson, Nateka L., Frost, Andra R., Grizzle, William E., Shcherbakov, Oleg D., Choi, Hyoungsoo, Meng, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868104/
https://ncbi.nlm.nih.gov/pubmed/20233590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2010.03.006
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