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Hallmarks and Determinants of Oncogenic Translation Revealed by Ribosome Profiling in Models of Breast Cancer()

Gene expression is extensively and dynamically modulated at the level of translation. How cancer cells prioritize the translation of certain mRNAs over others from a pool of competing mRNAs remains an open question. Here, we analyze translation in cell line models of breast cancer and normal mammary...

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Pubblicato in:Transl Oncol
Autori principali: Vaklavas, Christos, Blume, Scott W., Grizzle, William E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948383/
https://ncbi.nlm.nih.gov/pubmed/31911279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.12.002
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