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Hypoxia-dependent regulation of inflammatory pathways in immune cells

Uncontrolled inflammation underpins a diverse range of diseases where effective therapy remains an unmet clinical need. Hypoxia is a prominent feature of the inflammatory microenvironment that regulates key transcription factors including HIF and NF-κB in both innate and adaptive immune cells. In tu...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Taylor, Cormac T., Doherty, Glen, Fallon, Padraic G., Cummins, Eoin P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096820/
https://ncbi.nlm.nih.gov/pubmed/27454299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84433
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