Progesterone Attenuates Microglial-Driven Retinal Degeneration and Stimulates Protective Fractalkine-CX3CR1 Signaling

Retinitis pigmentosa (RP) is a degenerative disease leading to photoreceptor cell loss. Mouse models of RP, such as the rd10 mouse (B6.CXBl-Pde6brd10/J), have enhanced our understanding of the disease, allowing for development of potential therapeutics. In 2011, our group first demonstrated that the...

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Foilsithe in:PLoS One
Main Authors: Roche, Sarah L., Wyse-Jackson, Alice C., Gómez-Vicente, Violeta, Lax, Pedro, Ruiz-Lopez, Ana M., Byrne, Ashleigh M., Cuenca, Nicolás, Cotter, Thomas G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2016
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096718/
https://ncbi.nlm.nih.gov/pubmed/27814376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165197
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