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Knockout of fractalkine receptor Cx3cr1 does not alter disease or microglial activation in prion-infected mice

Microglial activation is a hallmark of the neuroimmunological response to Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis and prion disease. The CX3C chemokine axis consists of fractalkine (CX3CL1) and its receptor (CX3CR1); these are expressed by neurons and microglia respec...

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Detalhes bibliográficos
Publicado no:J Gen Virol
Main Authors: Striebel, James F., Race, Brent, Carroll, James A., Phillips, Katie, Chesebro, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042093/
https://ncbi.nlm.nih.gov/pubmed/26935332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000442
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