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Fractalkine-CX3CR1 signaling is critical for progesterone-mediated neuroprotection in the retina
Retinitis pigmentosa (RP) encompasses a group of retinal diseases resulting in photoreceptor loss and blindness. We have previously shown in the rd10 mouse model of RP, that rd10 microglia drive degeneration of viable neurons. Norgestrel, a progesterone analogue, primes viable neurons against potent...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5316933/ https://ncbi.nlm.nih.gov/pubmed/28216676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43067 |
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