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Fractalkine-CX3CR1 signaling is critical for progesterone-mediated neuroprotection in the retina
Retinitis pigmentosa (RP) encompasses a group of retinal diseases resulting in photoreceptor loss and blindness. We have previously shown in the rd10 mouse model of RP, that rd10 microglia drive degeneration of viable neurons. Norgestrel, a progesterone analogue, primes viable neurons against potent...
Enregistré dans:
| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5316933/ https://ncbi.nlm.nih.gov/pubmed/28216676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43067 |
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