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A Semiparametric Response Surface Model for Assessing Drug Interaction

When multiple drugs are administered simultaneously, investigators are often interested in assessing whether the drug combinations are synergistic, additive, or antagonistic. Existing response surface models are not adequate to capture the complex patterns of drug interactions. We propose a two-comp...

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Detalhes bibliográficos
Publicado no:Biometrics
Main Authors: Kong, Maiying, Lee, J. Jack
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096313/
https://ncbi.nlm.nih.gov/pubmed/17900314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1541-0420.2007.00882.x
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