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A Fluorescent Probe for Imaging Sirtuin Activity in Living Cells, Based on One‐Step Cleavage of the Dabcyl Quencher
Sirtuins (SIRTs) are a family of NAD(+)‐dependent histone deacetylases. In mammals, dysfunction of SIRTs is associated with age‐related metabolic diseases and cancers, so SIRT modulators are considered attractive therapeutic targets. However, current screening methodologies are problematic, and no t...
Gorde:
| Argitaratua izan da: | Chembiochem |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
John Wiley and Sons Inc.
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5095863/ https://ncbi.nlm.nih.gov/pubmed/27542094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600374 |
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