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Synthesis of artificial substrate based on inhibitor for detecting LSD1 activity

Lysine methylation is one of the most important modification, which is regulated by histone lysine methyltransferases and histone lysine demethylases. Lysine-specific demethylase 1 (LSD1) specifically demethylates mono- and dimethyl-lysine on histone H3 (H3K4Me/Me(2), H3K9Me/Me(2)) to control chroma...

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Detalhes bibliográficos
Publicado no:J Clin Biochem Nutr
Main Authors: Ohta, Yuhei, Kawaguchi, Mitsuyasu, Ieda, Naoya, Nakagawa, Hidehiko
Formato: Artigo
Idioma:Inglês
Publicado em: the Society for Free Radical Research Japan 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533851/
https://ncbi.nlm.nih.gov/pubmed/33041512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.20-9
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