Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy

Cancer cells express tumour-specific antigens derived via genetic and epigenetic alterations, which may be targeted by T-cell-mediated immune responses. However, cancer cells can avoid immune surveillance by suppressing immunity through activation of specific inhibitory signalling pathways, referred...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Lee, Ju Yeon, Lee, Hyun Tae, Shin, Woori, Chae, Jongseok, Choi, Jaemo, Kim, Sung Hyun, Lim, Heejin, Won Heo, Tae, Park, Kyeong Young, Lee, Yeon Ji, Ryu, Seong Eon, Son, Ji Young, Lee, Jee Un, Heo, Yong-Seok
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095608/
https://ncbi.nlm.nih.gov/pubmed/27796306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13354
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