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Structural Biology of the TNFα Antagonists Used in the Treatment of Rheumatoid Arthritis
The binding of the tumor necrosis factor α (TNFα) to its cognate receptor initiates many immune and inflammatory processes. The drugs, etanercept (Enbrel(®)), infliximab (Remicade(®)), adalimumab (Humira(®)), certolizumab-pegol (Cimzia(®)), and golimumab (Simponi(®)), are anti-TNFα agents. These dru...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5877629/ https://ncbi.nlm.nih.gov/pubmed/29518978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030768 |
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