ロード中...

Bromodomain and Extraterminal Protein Inhibition Blocks Growth of Triple-negative Breast Cancers through the Suppression of Aurora Kinases

Bromodomain and extraterminal (BET) proteins are epigenetic “readers” that recognize acetylated histones and mark areas of the genome for transcription. BRD4, a BET family member protein, has been implicated in a number of types of cancer, and BET protein inhibitors (BETi) are efficacious in many pr...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Sahni, Jennifer M., Gayle, Sylvia S., Bonk, Kristen L. Weber, Vite, Leslie Cuellar, Yori, Jennifer L., Webb, Bryan, Ramos, Erika K., Seachrist, Darcie D., Landis, Melissa D., Chang, Jenny C., Bradner, James E., Keri, Ruth A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095428/
https://ncbi.nlm.nih.gov/pubmed/27650498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.738666
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!