Targeted sequencing identifies genetic alterations that confer primary resistance to EGFR tyrosine kinase inhibitor (Korean Lung Cancer Consortium)

BACKGROUND: Non-small-cell lung cancer (NSCLC) patients with activating epidermal growth factor receptor (EGFR) mutations may exhibit primary resistance to EGFR tyrosine kinase inhibitor (TKI). We aimed to examine genomic alterations associated with de novo resistance to gefitinib in a prospective s...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lim, Sun Min, Kim, Hye Ryun, Cho, Eun Kyung, Min, Young Joo, Ahn, Jin Seok, Ahn, Myung-Ju, Park, Keunchil, Cho, Byoung Chul, Lee, Ji-Hyun, Jeong, Hye Cheol, Kim, Eun Kyung, Kim, Joo-Hang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095002/
https://ncbi.nlm.nih.gov/pubmed/27121209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8904
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