Targeted sequencing identifies genetic alterations that confer primary resistance to EGFR tyrosine kinase inhibitor (Korean Lung Cancer Consortium)

BACKGROUND: Non-small-cell lung cancer (NSCLC) patients with activating epidermal growth factor receptor (EGFR) mutations may exhibit primary resistance to EGFR tyrosine kinase inhibitor (TKI). We aimed to examine genomic alterations associated with de novo resistance to gefitinib in a prospective s...

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Vydáno v:Oncotarget
Hlavní autoři: Lim, Sun Min, Kim, Hye Ryun, Cho, Eun Kyung, Min, Young Joo, Ahn, Jin Seok, Ahn, Myung-Ju, Park, Keunchil, Cho, Byoung Chul, Lee, Ji-Hyun, Jeong, Hye Cheol, Kim, Eun Kyung, Kim, Joo-Hang
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095002/
https://ncbi.nlm.nih.gov/pubmed/27121209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8904
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