Longitudinal monitoring of EGFR mutations in plasma predicts outcomes of NSCLC patients treated with EGFR TKIs: Korean Lung Cancer Consortium (KLCC-12-02)

We hypothesized that plasma-based EGFR mutation analysis for NSCLC may be feasible for monitoring treatment response to EGFR TKIs and also predict drug resistance. Clinically relevant mutations including exon 19 deletion (ex19del), L858R and T790M were analyzed using droplet digital PCR (ddPCR) in l...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Lee, Ji Yun, Qing, Xu, Xiumin, Wei, Yali, Bai, Chi, Sangah, Bak, So Hyeon, Lee, Ho Yun, Sun, Jong-Mu, Lee, Se-Hoon, Ahn, Jin Seok, Cho, Eun Kyung, Kim, Dong-Wan, Kim, Hye Ryun, Min, Young Joo, Jung, Sin-Ho, Park, Keunchil, Mao, Mao, Ahn, Myung-Ju
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872763/
https://ncbi.nlm.nih.gov/pubmed/26755650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6874
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