Longitudinal monitoring of EGFR mutations in plasma predicts outcomes of NSCLC patients treated with EGFR TKIs: Korean Lung Cancer Consortium (KLCC-12-02)

We hypothesized that plasma-based EGFR mutation analysis for NSCLC may be feasible for monitoring treatment response to EGFR TKIs and also predict drug resistance. Clinically relevant mutations including exon 19 deletion (ex19del), L858R and T790M were analyzed using droplet digital PCR (ddPCR) in l...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Lee, Ji Yun, Qing, Xu, Xiumin, Wei, Yali, Bai, Chi, Sangah, Bak, So Hyeon, Lee, Ho Yun, Sun, Jong-Mu, Lee, Se-Hoon, Ahn, Jin Seok, Cho, Eun Kyung, Kim, Dong-Wan, Kim, Hye Ryun, Min, Young Joo, Jung, Sin-Ho, Park, Keunchil, Mao, Mao, Ahn, Myung-Ju
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872763/
https://ncbi.nlm.nih.gov/pubmed/26755650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6874
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