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Hepatic cytochromes P450: Structural degrons and barcodes, posttranslational modifications and cellular adapters in the ERAD-endgame
The endoplasmic reticulum (ER)-anchored hepatic cytochromes P450 (P450s) are enzymes that metabolize endo- and xenobiotics i.e. drugs, carcinogens, toxins, natural and chemical products. These agents modulate liver P450 content through increased synthesis or reduction via inactivation and/or proteol...
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| Publicado no: | Drug Metab Rev |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5094896/ https://ncbi.nlm.nih.gov/pubmed/27320797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/03602532.2016.1195403 |
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