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C. elegans GLP-1/Notch activates transcription in a probability gradient across the germline stem cell pool
C. elegans Notch signaling maintains a pool of germline stem cells within their single-celled mesenchymal niche. Here we investigate the Notch transcriptional response in germline stem cells using single-molecule fluorescence in situ hybridization coupled with automated, high-throughput quantitation...
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Publicado no: | eLife |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
eLife Sciences Publications, Ltd
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5094854/ https://ncbi.nlm.nih.gov/pubmed/27705743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18370 |
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