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C. elegans GLP-1/Notch activates transcription in a probability gradient across the germline stem cell pool

C. elegans Notch signaling maintains a pool of germline stem cells within their single-celled mesenchymal niche. Here we investigate the Notch transcriptional response in germline stem cells using single-molecule fluorescence in situ hybridization coupled with automated, high-throughput quantitation...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Lee, ChangHwan, Sorensen, Erika B, Lynch, Tina R, Kimble, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094854/
https://ncbi.nlm.nih.gov/pubmed/27705743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18370
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