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Cell-cycle quiescence maintains Caenorhabditis elegans germline stem cells independent of GLP-1/Notch

Many types of adult stem cells exist in a state of cell-cycle quiescence, yet it has remained unclear whether quiescence plays a role in maintaining the stem cell fate. Here we establish the adult germline of Caenorhabditis elegans as a model for facultative stem cell quiescence. We find that mitoti...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Seidel, Hannah S, Kimble, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718729/
https://ncbi.nlm.nih.gov/pubmed/26551561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10832
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