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Sexual dimorphism of niche architecture and regulation of the Caenorhabditis elegans germline stem cell pool

Stem cell maintenance by niche signaling is a common theme across phylogeny. In the Caenorhabditis elegans gonad, the broad outlines of germline stem cell (GSC) regulation are the same for both sexes: GLP-1/Notch signaling from the mesenchymal distal tip cell niche maintains GSCs in the distal gonad...

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Pubblicato in:Mol Biol Cell
Autori principali: Crittenden, Sarah L., Lee, ChangHwan, Mohanty, Ipsita, Battula, Sindhu, Knobel, Karla, Kimble, Judith
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727753/
https://ncbi.nlm.nih.gov/pubmed/31067147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-03-0164
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