MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders

Numerous genetic variants associated with MEF2C are linked to autism, intellectual disability (ID) and schizophrenia (SCZ) – a heterogeneous collection of neurodevelopmental disorders with unclear pathophysiology. MEF2C is highly expressed in developing cortical excitatory neurons, but its role in t...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Harrington, Adam J, Raissi, Aram, Rajkovich, Kacey, Berto, Stefano, Kumar, Jaswinder, Molinaro, Gemma, Raduazzo, Jonathan, Guo, Yuhong, Loerwald, Kris, Konopka, Genevieve, Huber, Kimberly M, Cowan, Christopher W
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094851/
https://ncbi.nlm.nih.gov/pubmed/27779093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20059
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