Postsynaptic FMRP bi-directionally regulates excitatory synapses as a function of developmental age and MEF2 activity

Rates of synapse formation and elimination change over the course of postnatal development, but little is known of molecular mechanisms that mediate this developmental switch. Here we report that the dendritic RNA binding protein Fragile X Mental Retardation Protein (FMRP) bi-directionally and cell...

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Hauptverfasser: Zang, Tong, Maksimova, Marina A., Cowan, Christopher W., Bassel-Duby, Rhonda, Olson, Eric N., Huber, Kimberly M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715571/
https://ncbi.nlm.nih.gov/pubmed/23511190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2013.03.002
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