Pre-Existing HCV Variants Resistant to DAAs and Their Sensitivity to PegIFN/RBV in Chinese HCV Genotype 1b Patients

BACKGROUND: The efficacy of direct-acting antiviral agents (DAAs) could be attenuated by the presence of resistance-associated variants (RAVs). The aim of this study was to investigate the natural prevalence of RAVs among Chinese HCV genotype 1b patients and analyze the efficacy of pegylated interfe...

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Publicado en:PLoS One
Autores principales: Zhang, Yu, Cao, Ying, Zhang, Renwen, Zhang, Xiaxia, Lu, Haiying, Wu, Chihong, Huo, Na, Xu, Xiaoyuan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094756/
https://ncbi.nlm.nih.gov/pubmed/27812165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165658
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